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Unlike approved agents such as semaglutide (Wegovy) or tirzepatide (Zepbound), retatrutide has not yet received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) for use in the United Kingdom

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It is a naturally occurring compound that has been suggested to add support in cell growth and regulation, and cell death, particularly in the case of vascular endothelial cells (the innermost layer of blood vessels)